ONC201 in combination with paxalisib for the treatment of H3K27-altered diffuse midline glioma
- Creator: Jackson, Evangeline R. , Duchatel, Ryan J. , Le Grand, Marion , Kearney, Padraic S. , Douglas, Alicia M. , Findlay, Izac J. , Germon, Zacary P. , McEwen, Holly P. , Beitaki, Tyrone S. , Patabendige, Adjanie , Skerrett-Byrne, David A. , Nixon, Brett , Staudt, Dilana E. , Smith, Nathan D. , Day, B , Manoharan, N , Nagabushan, S , Hansford, JR , Govender, D , McCowage, GB , Firestein, R , Howlett, M , Endersby, R , Persson, Mika L. , Gottardo, NG , Alvaro, F , Waszak, SM , Larsen, MR , Colino-Sanguino, Y , Valdés-Mora, F , Rakotomalala, A , Meignan, S , Pasquier, E , Andre, N , Mannan, Abdul , Hulleman, E , Eisenstat, DD , Vitanza, NA , Nazarian, J , Koschmann, C , Mueller, S , Cain, JE , Dun, MD , Yadavilli, Sridevi , Parackal, Sarah , Game, Shaye , Chong, Wai Chin , Jayasekara, W. Samantha N.
- Resource Type: journal article
- Date: 2023
Pan-Cancer Analysis of Canonical and Modified miRNAs Enhances the Resolution of the Functional miRNAome in Cancer
- Creator: Distefano, Rosario , Tomasello, Luisa , Ma, Qin , Nigita, Giovanni , Croce, Carlo M. , Rampioni Vinciguerra, Gian Luca , Gasparini, Pierluigi , Xiang, Yujia , Bagnoli, Marina , Marceca, Gioacchino P. , Fadda, Paolo , Laganà, Alessandro , Acunzo, Mario
- Resource Type: journal article
- Date: 2022
The emerging roles of rna m6a methylation and demethylation as critical regulators of tumorigenesis, drug sensitivity, and resistance
- Creator: Lan, Qing , Liu, Pei Y. , Bell, Jessica L. , Wang, Jenny Y. , Hüttelmaier , Stefan , Zhang, Xu Dong , Zhang, Lirong , Liu, Tao
- Resource Type: journal article
- Date: 2021
A p53-responsive miRNA network promotes cancer cell quiescence
- Creator: La, Ting , Liu, Guang Zhi , Guo, Su Tang , Liu, Tao , Thorne, Rick F. , Jin, Lei , Zhang, Xu Dong , Farrelly, Margaret , Cole, Nicole , Feng, Yu Chen , Zhang, Yuan Yuan , Sherwin, Simonne K. , Yari, Hamed , Tabatabaee, Hessam , Yan, Xu Guang
- Resource Type: journal article
- Date: 2018
Skp2-mediated stabilization of MTH1 promotes survival of melanoma cells upon oxidative stress
- Creator: Wang, Jia Yu , Liu, Guang Zhi , Jin, Lei , Wilmott, James S. , La, Ting , Feng, Yu Chen , Yari, Hamed , Yan, Xu Guang , Thorne, Rick F. , Scolyer, Richard A. , Zhang, Xu Dong
- Resource Type: journal article
- Date: 2017
The histone methyltransferase DOT1L promotes neuroblastoma by regulating gene transcription
- Creator: Wong, Matthew , Tee, Andrew E. L. , Liu, Pei Yan , Zhang, Xu Dong , Hüttelmaier, Stefan , Wong, Jason W. H. , Wang, Jenny , Polly, Patsie , Perini, Giovanni , Scarlett, Christopher J. , Liu, Tao , Milazzo, Giorgio , Bell, Jessica L. , Poulos, Rebecca C. , Atmadibrata, Bernard , Sun, Yuting , Jing, Duohui , Ho, Nicholas , Ling, Dora
- Resource Type: journal article
- Date: 2017
Stomach-specific activation of oncogenic KRAS and STAT3-dependent inflammation cooperatively promote gastric tumorigenesis in a preclinical model
- Creator: Thiem, Stefan , Eissmann, Moritz F. , Waring, Paul , Buchert, Michael , Jarnicki, Andrew , Ernst, Matthias , Elzer, Joachim , Jonas, Anna , Putoczki, Tracy L. , Poh, Ashleigh , Nguyen, Paul , Preaudet, Adele , Flanagan, Dustin , Vincan, Elizabeth
- Resource Type: journal article
- Date: 2016
Nerve-cancer cell cross-talk: a novel promoter of tumor progression
- Creator: Jobling, Phillip , Pundavela, Jay , Oliveira, Sonia M. R. , Roselli, Séverine , Walker, Marjorie M. , Hondermarck, Hubert
- Resource Type: journal article
- Date: 2015
A novel class of anticancer compounds targets the actin cytoskeleton in tumor cells
- Creator: Stehn, Justine R. , Haass, Nikolas K. , Allanson, Munif , Fath, Thomas , Hill, Timothy A. , McCluskey, Adam , Schevzov, Galina , Palmer, Stephen J. , Hardeman, Edna C. , Winlaw, David , Reeve, Vivienne E. , Dixon, Ian , Bonello, Teresa , Weninger, Wolfgang , Cripe, Timothy P. , Gunning, Peter W. , Desouza, Melissa , Kottyan, Gregg , Treutlein, Herbert , Zeng, Jun , Nascimento, Paula R. B. B. , Sequeira, Vanessa B. , Butler, Tanya L.
- Resource Type: journal article
- Date: 2013
Essential requirement for PP2A inhibition by the oncogenic receptor c-KIT suggests PP2A reactivation as a strategy to treat c-KIT⁺ cancers
- Creator: Roberts, Kathryn G. , Smith, Amanda M. , Sim, Alistair T. R. , Ashman, Leonie K. , Verrills, Nicole M. , McDougall, Fiona , Carpenter, Helen , Horan, Martin , Neviani, Paolo , Powell, Jason A. , Thomas, Daniel , Guthridge, Mark A. , Perrotti, Danilo
- Resource Type: journal article
- Date: 2010
Nucleotide excision repair gene expression after cisplatin treatment in melanoma
- Creator: Bowden, Nikola A. , Ashton, Katie A. , Kiejda, Kelly A. , Zhang, Xu Dong , Hersey, Peter , Scott, Rodney J.
- Resource Type: journal article
- Date: 2010
Inhibition of endoplasmic reticulum stress-induced apoptosis of melanoma cells by the ARC protein
- Creator: Chen, Li Hua , Jiang, Chen Chen , Watts, Ralph , Thorne, Rick F. , Kiejda, Kelly A. , Zhang, Xu Dong , Hersey, Peter
- Resource Type: journal article
- Date: 2008
Up-regulation of Mcl-1 is critical for survival of human melanoma cells upon endoplasmic reticulum stress
- Creator: Jiang, Chen Chen , Lucas, Keryn , Avery-Kiejda, Kelly A. , Wade, Margaret , deBock, Charles E. , Thorne, Rick F. , Allen, John , Hersey, Peter , Zhang, Xu Dong
- Resource Type: journal article
- Date: 2008
An in vivo tumor model exploiting metabolic response as a biomarker for targeted drug development
- Creator: Cullinane, Carleen , Dorow, Donna S. , Kansara, Maya , Conus, Nelly , Binns, David , Hicks, Rodney J. , Ashman, Leonie Kay , McArthur, Grant A. , Thomas, David M.
- Resource Type: journal article
- Date: 2005
An in vivo tumor model exploiting metabolic response as a biomarker for targeted drug development
- Creator: Cullinane, C. , Dorow, D. S. , Kansara, M. , Conus, N. , Binns, D. , Hicks, R. J. , Ashman, Leonie K. , McArthur, G. A. , Thomas, D. M.
- Resource Type: journal article
- Date: 2005
CDKN2A common variants and their association with melanoma risk: A population-based study
- Creator: Debniak, T. , Scott, Rodney J. , Huzarski, T. , Byrski, T. , Rozmiarek, A. , Debniak, B. , Zaluga, E. , Maleszka, R. , Kladny, J. , Gorski, B. , Cybulski, C. , Gronwald, J. , Kurzawski, G. , Lubinski, J.
- Resource Type: journal article
- Date: 2005
The antifolate activity of tea catechins (letter)
- Creator: Lucock, Mark D. , Roach, Paul D.
- Resource Type: journal article
- Date: 2005
The NOD2 3020insC mutation and the risk of colorectal cancer
- Creator: Kurzawski, Grzegorz , Suchy, Janina , Domagala, Wenancjusz , Scott, Rodney J. , Lubinski, Jan , Kladny, Jozef , Grabowska, Ewa , Mierzejewski, Marek , Jakubowska, Anna , Debniak, Tadeusz , Cybulski, Cezary , Kowalska, Elsbieta , Szych, Zbigniew
- Resource Type: journal article
- Date: 2004
A CD44 survival pathway triggers chemoresistance via lyn kinase and phosphoinositide 3-kinase/Akt in colon carcinoma cells
- Creator: Bates, Richard C. , Edwards, Nathaniel S. , Burns, Gordon F. , Fisher, David E.
- Resource Type: journal article
- Date: 2001